For IV administration, the drug must be in which form?

• A. Aqueous solution
• B. Oil suspension
• C. Gas form
• D. Solid crystalline form

Answer: (A)

Intravenous administration requires the drug to be in an aqueous solution because the bloodstream is an aqueous environment and the medication must be readily dissolved to mix with blood and distribute quickly and predictably. An aqueous solution avoids particulate matter that could irritate or obstruct vessels, reducing the risk of embolism. It also allows proper control of dose, isotonicity, and sterility for safe IV use.

Other forms pose problems: an oil suspension contains undissolved particles that may not distribute evenly and could cause embolic complications or require emulsification; a gas form could lead to air embolism; and a solid crystalline form would not dissolve, risking vessel blockage and unreliable dosing. Hence, an aqueous solution is the appropriate form for IV delivery.