Which drug class will increase gastric emptying rate?

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Study for the Pharmaceutics Xenobiotics Across Bio Membrane Test. Prepare with flashcards and multiple-choice questions, each providing hints and explanations. Get ready for your pharmacy exam!

Multiple Choice

Which drug class will increase gastric emptying rate?

Explanation:
Activation of the parasympathetic nervous system via cholinergic mechanisms increases GI motility and speeds gastric emptying. Acetylcholine stimulates muscarinic receptors in the stomach and intestines, boosting smooth muscle contractions and peristaltic activity, which accelerates the movement of content from the stomach into the small intestine. Anticholinergic drugs block acetylcholine and therefore reduce motility, slowing emptying. Beta-adrenergic agonists activate sympathetic pathways that generally inhibit GI movements and slow emptying. Opioid receptor agonists increase sphincter tone and dampen peristalsis, also slowing gastric emptying.

Activation of the parasympathetic nervous system via cholinergic mechanisms increases GI motility and speeds gastric emptying. Acetylcholine stimulates muscarinic receptors in the stomach and intestines, boosting smooth muscle contractions and peristaltic activity, which accelerates the movement of content from the stomach into the small intestine.

Anticholinergic drugs block acetylcholine and therefore reduce motility, slowing emptying. Beta-adrenergic agonists activate sympathetic pathways that generally inhibit GI movements and slow emptying. Opioid receptor agonists increase sphincter tone and dampen peristalsis, also slowing gastric emptying.

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