Which of the following is NOT a recommended characteristic of subcutaneous injections?

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Study for the Pharmaceutics Xenobiotics Across Bio Membrane Test. Prepare with flashcards and multiple-choice questions, each providing hints and explanations. Get ready for your pharmacy exam!

Multiple Choice

Which of the following is NOT a recommended characteristic of subcutaneous injections?

Explanation:
Subcutaneous injections work best when the volume is small, the solution is isotonic, and the pH is close to physiological. The tissue under the skin can accommodate only a limited amount of fluid before it becomes distended and painful, and larger volumes can lead to slower, uneven absorption and local tissue irritation. Because of that, high volumes (greater than about 3 mL) are not recommended for subcutaneous administration. Keeping volumes under this limit, along with isotonic solutions and a near-physiologic pH, helps ensure comfort and predictable uptake.

Subcutaneous injections work best when the volume is small, the solution is isotonic, and the pH is close to physiological. The tissue under the skin can accommodate only a limited amount of fluid before it becomes distended and painful, and larger volumes can lead to slower, uneven absorption and local tissue irritation. Because of that, high volumes (greater than about 3 mL) are not recommended for subcutaneous administration. Keeping volumes under this limit, along with isotonic solutions and a near-physiologic pH, helps ensure comfort and predictable uptake.

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