Which skin region has a higher penetration ratio due to a thinner stratum corneum?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Study for the Pharmaceutics Xenobiotics Across Bio Membrane Test. Prepare with flashcards and multiple-choice questions, each providing hints and explanations. Get ready for your pharmacy exam!

Multiple Choice

Which skin region has a higher penetration ratio due to a thinner stratum corneum?

Explanation:
Penetration through the skin is largely governed by the stratum corneum, the outermost barrier. A thinner stratum corneum offers less resistance to diffusion, so more of the drug can pass per unit area. Among common skin sites, the scrotum has a very thin stratum corneum, making it significantly more permeable. The heel has a thick stratum corneum, providing strong resistance to penetration; the palm is also thick and keratinized, and the back of the forearm is of intermediate thickness. Because of its notably thinner barrier, the scrotum shows a higher penetration ratio.

Penetration through the skin is largely governed by the stratum corneum, the outermost barrier. A thinner stratum corneum offers less resistance to diffusion, so more of the drug can pass per unit area. Among common skin sites, the scrotum has a very thin stratum corneum, making it significantly more permeable. The heel has a thick stratum corneum, providing strong resistance to penetration; the palm is also thick and keratinized, and the back of the forearm is of intermediate thickness. Because of its notably thinner barrier, the scrotum shows a higher penetration ratio.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy